1.           Sharma A, Weber B, Meibohm B. Long Pulmonary Residence Time and Plasma Half-Life of Tiotropium: Implications for Pharmacokinetic Bioequivalence Studies. Clin Drug Investig 2017;37:705.

 

2.           Sharma A, Kerstjens HA, Aalbers R, Moroni-Zentgraf P, Weber B, Dahl R. Pharmacokinetics of tiotropium administered by Respimat(R) in asthma patients: Analysis of pooled data from phase II and III clinical trials. Pulm Pharmacol Ther. 2016.

 

3.           Nguyen TH, Mouksassi MS, Holford N, Al-Huniti N, Freedman I, Hooker AC, John J, Karlsson MO, Mould DR, Perez Ruixo JJ, Plan EL, Savic R, van Hasselt JG, Weber B, Zhou C, Comets E, Mentre F, Model Evaluation Group of the International Society of Pharmacometrics IBPC. Model evaluation of continuous data pharmacometric models: Metrics and graphics. CPT Pharmacometrics Syst Pharmacol. 2016.

 

4.           Weber B, Borghardt JM, Parra-Guillen ZP, Sharma A, Retlich S, Staab A, Troconiz IF. Tiotropium Pharmacokinetics and Pharmacodynamics - What are Drivers for Systemic Levels and Local Pulmonary Responses? Respiratory Drug Delivery 2016. 2016;1:45-54.

 

5.           Borghardt JM, Weber B, Staab A, Kunz C, Kloft C. Model-based evaluation of pulmonary pharmacokinetics in asthmatic and COPD patients after oral olodaterol inhalation. Br J Clin Pharmacol. 2016;82:739-53.

 

6.           Borghardt JM, Weber B, Staab A, Kunz C, Formella S, Kloft C. Investigating pulmonary and systemic pharmacokinetics of inhaled olodaterol in healthy volunteers using a population pharmacokinetic approach. Br J Clin Pharmacol. 2016;81:538-52.

 

7.           Sharma A, Weber B, Wein M, Hallmann C, Meibohm B. Essential criteria for pharmacokinetic studies supporting bioequivalence of inhaled tiotropium bromide products. Clin Pharmacol Drug Dev. 2016;5:52-6.

 

8.           Weber B, Hochhaus G. A Systematic Analysis of the Sensitivity of Plasma Pharmacokinetics to Detect Differences in the Pulmonary Performance of Inhaled Fluticasone Propionate Products Using a Model-Based Simulation Approach. AAPS J. 2015;17:999-1010.

 

9.           Weber B, Lee SL, Delvadia R, Lionberger R, Li BV, Tsong Y, Hochhaus G. Application of the modified chi-square ratio statistic in a stepwise procedure for cascade impactor equivalence testing. AAPS J. 2015;17:370-9.

 

10.         Borghardt JM, Weber B, Staab A, Kloft C. Pharmacometric Models for Characterizing the Pharmacokinetics of Orally Inhaled Drugs. AAPS J. 2015;17:853-70.

 

11.         Borghardt JM, Weber B, Staab A, Kloft C. Impact of Pulmonary Dissolution and Pulmonary Absorption Processes on the Pulmonary and Systemic Pharmacokinetics of Inhaled Drugs: An In Silico Analysis. RDD Europe 2015. 2015;2:299-304.

 

12.         Weber B, Troconiz IF, Borghardt JM, Staab A, Sharma A. Model-Based Evaluation of Single and Multiple Dose Pharmacokinetics of Inhaled Tiotropium in Healthy Volunteers and Implications for Systemic Exposure Studies. RDD Europe 2015. 2015;2:249-54.

 

13.         Leiner S, Weber B. Is the EMA Guideline on Therapeutic Equivalence of Inhalation Products Up to Date? RDD Europe 2015. 2015;2:245-8.

 

14.         Hurtado FK, Weber B, Derendorf H, Hochhaus G, Dalla Costa T. Population pharmacokinetic modeling of the unbound levofloxacin concentrations in rat plasma and prostate tissue measured by microdialysis. Antimicrob Agents Chemother. 2014;58:678-86.

 

15.         Borghardt JM, Weber B, Staab A, Kunz C, Schiewe J, Kloft C. Expanding the Mechanistic Knowledge About Pulmonary Absorption Processes Using a Population Pharmacokinetic Model for Inhaled Olodaterol. Respiratory Drug Delivery 2014. 2014;2:417-22.

 

16.         Weber B, Lee SL, Lionberger R, Li BV, Tsong Y, Hochhaus G. A sensitivity analysis of the modified chi-square ratio statistic for equivalence testing of aerodynamic particle size distribution. AAPS J. 2013;15:465-76.

 

17.         Weber B, Hochhaus G, Adams W, Lionberger R, Li B, Tsong Y, Lee SL. A Stability Analysis of a Modified Version of the Chi-Square Ratio Statistic: Implications for Equivalence Testing of Aerodynamic Particle Size Distribution. AAPS J. 2013;15:1-9.

 

18.         Weber B, Hochhaus G. A pharmacokinetic simulation tool for inhaled corticosteroids. AAPS J. 2013;15:159-71.

 

19.         Scherliess R, Buske S, Young K, Weber B, Rades T, Hook S. In vivo evaluation of chitosan as an adjuvant in subcutaneous vaccine formulations. Vaccine. 2013;31:4812-9.

 

20.         Weber B, Adams W, Lionberger R, Li B, Tsong Y, Hochhaus G, Lee SL. Evaluation of Statistical Methods for Determining Equivalence of Aerodynamic Particle Size Distribution. Respiratory Drug Delivery 2012. 2012;3:803-8.

 

21.         Haug KG, Weber B, Hochhaus G, Butterweck V. Nonlinear pharmacokinetics of visnagin in rats after intravenous bolus administration. Eur J Pharm Sci. 2012;45:79-89.

 

22.         Haug KG, Weber B, Hochhaus G, Butterweck V. Pharmacokinetic evaluation of visnagin and Ammi visnaga aqueous extract after oral administration in rats. Planta Med. 2012;78:1831-6.

 

23.         Wu K, Blomgren AL, Ekholm K, Weber B, Edsbaecker S, Hochhaus G. Budesonide and ciclesonide: effect of tissue binding on pulmonary receptor binding. Drug Metab Dispos. 2009;37:1421-6.